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Effects of 12 Weeks of Combined Exercise on Vascular Function-Related Inflammation Factors, Carotid Intima-Media Thickness and Physical Fitness in Obese 40s-Aged Women with Metabolic Syndrome
Korean J Sports Med 2019;37:184-194
Published online December 1, 2019;  https://doi.org/10.5763/kjsm.2019.37.4.184
© 2019 The Korean Society of Sports Medicine.

Kijin Kim

Department of Physical Education, College of Physical Education, Keimyung University, Daegu, Korea
Correspondence to: Kijin Kim
Department of Physical Education, College of Physical Education, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu 42601, Korea
Tel: +82-53-580-5256, Fax: +82-53-580-5314, E-mail: Kjk744@kmu.ac.kr
Received November 5, 2019; Revised November 28, 2019; Accepted November 29, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Purpose: The purpose of this study was to investigate the effects of 12 weeks of combined exercise on vascular function-related inflammation, carotid intima-media thickness and fitness factors in obese middle-aged women with metabolic syndrome.
Methods: The subjects of this study were 40 middle-aged women in their 40s with metabolic syndrome but no specific disease. The exercise group performed aerobic exercise and resistance exercise five times a week for 12 weeks, and then measured body composition, blood pressure, vascular function-related inflammation factors, metabolic syndrome factors, carotid intima-media thickness, and physical factors.
Results: The exercise group showed a significant (p<0.05) reduction after exercise in all items related to body composition, systolic and diastolic blood pressure, and intima-media thickness of the right carotid and left carotid arteries. Exercise group showed a significant decrease (p<0.05) after exercise in interleukin-6, tumor necrosis factor-慣, leptin, and all items of glucose metabolism-related variables. The exercise group showed a significant (p<0.05) increase after exercise physical efficiency index, grip strength, sit-ups, and sit & reach. After 12 weeks of exercise training, the reduction of intima-media thickness of the carotid artery was significantly (p<0.05) correlated with the improvement of body weight, systolic and diastolic blood pressure, grip and sit & reach, blood HbA1c, and triglyceride concentration.
Conclusion: In conclusion, metabolic syndrome improved the body composition, blood glucose metabolism and lipid variables after 12 weeks of combined exercise program for obese middle-aged women. Significant improvement in blood pressure and carotid endometrial thickness, which is a function-related indicator, was confirmed.
Keywords : Exercise, Intima-media thickness, Metabolic syndrome, Woman
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