The Korean Journal of Sports Medicine

Indexed in /covered by CAS, KoreaScience & DOI/Crossref:eISSN 2288-6028   pISSN 1226-3729

Table. 1.

Table. 1.

Clinical exercise prescription and cardiovascular health in breast cancer

Study Year Sample (n) and design Intervention Adherence (%) Cardiovascularoutcomes Treatment window
Brahmbhatt et al.26 2020 22
Pilot
Hospital-based
31 days, brisk walking 3−5 days/wk for 30−40 min/session, and 2−3 sets of 10−12 repetitions/exercise, (standing rows, shoulder external rotation, front raise, lateral raise, bicep curls, triceps extensions, wall push-ups, and chest press) training 2–3 days/wk 76 Increased in the 6-min walk distance (+57 m) Before therapy
MacVicar et al.32 1989 45
RCT
Hospital-based
10 wk, aerobic interval training, cycle ergometer, 3 days/wk NA Increased in VO2peak During therapy
Segal et al.33 2001 123
RCT
Hospital-based
26 wk, aerobic exercise: 3 days/wk, 7−10 min warm-up, walking and cool-down, 2 additional days self-directed exercise at home 71.5 Increased in VO2peak (+3.5 mL/kg/min) During therapy
Courneya et al.17 2007 242
RCT
Hospital-based
17 wk, aerobic exercise: 3 days/wk, cycle ergometer, treadmill, or elliptical, beginning at 60% of their VO2max (wk 1 to 6) and progressing to 70% (wk 7 to 12) and 80% beyond wk 12. 70.2 Increased in VO2peak (+0.5 mL/kg/min) During therapy
Jones et al.34 2013 20
RCT
Hospital-based
12 wk, aerobic exercise: cycle ergometry, 3 days/wk at 60%−100% of VO2peak, 30−45 min/session 66 Increased in VO2peak (+2.6 mL/kg/min) and FMD (+0.7%) During therapy
Travier et al.35 2015 204
RCT
Hospital-based
18 wk, aerobic exercise: interval training of alternating intensity performed with a heart rate at (3×2 min increasing to 2×7 min) or below (3×4 min decreasing to 1×7 min) ventilatory threshold, based on heart rate and the Borg scale.
Strength training: arms, legs, shoulder, and trunk. 2×10 repetitions (65% one-repetition maximum) and gradually increased to reach 1×10 repetitions
83 No changes in VO2peak and peak power output During therapy
Hojan et al.36 2020 47
RCT
Hospital-based
9 wk, aerobic exercise: brisk walking, running on a treadmill, and cycling, 5 days/wk, 80% age-predicted maximum heart rate.
Resistance exercise sessions based on isometric, concentric, and eccentric training consisted of one to 3 sets of 8–10 repetitions of selected exercises in different positions for the trunk, upper body, and leg muscles
98.7 No changes in left ventricular ejection fraction and 6-min walk distance During therapy
Lee et al.31 2019 30
RCT
Hospital-based
8 wk, aerobic exercise: HIIT (1:2 ratio) on a cycle, 90% peak power output 3 days/wk, 30 min/session 82.3 Maintained VO2peak while control group reduced by 10%; significant change in FMD During therapy
Mijwel et al.37 2018 240
RCT
Hospital-based
16 wk, aerobic exercise: HIIT, 13−15 Borg scale, 2 days/wk. Resistance exercise: 2−3 sets of 8−12 repetitions at an intensity of 80% of the patients’ estimated 1-repetition maximum 63−68 Maintained VO2peak During therapy
Schulz et al.38 2018 26
RCT
6 wk, combined HIIT and strength training NA VO2peak+2% During therapy
Schneider et al.39 2007 113
Hospital-based
6 mo, 2−3 days/wk 60 min/session 10-min warm-up, 40-min aerobic (outdoor or treadmill walking, stationary cycling, stepping or walking), resistance exercise and stretching, 40%−75% of heart rate reserve 89.6 Improved systolic blood pressure and time on treadmill during therapy. Increased in pulmonary function and VO2max after therapy During or after therapy
Courneya et al.16 2003 53
RCT
Hospital-based
15-wk, cycle ergometers 3 days/wk for at a power output that elicited the ventilatory equivalent for carbon dioxide 98.4 Increased in VO2peak (+0.24 L/min) After therapy
Lee et al.18 2019 100
RCT
Hospital-based
16 wk, 3 days/wk aerobic (treadmill, cycle) and resistance exercise (leg press, leg flexions/extensions/ chest press, seated rows, biceps curls, triceps pulldown) at 60%−80% 1-repetition maximum 96 Reduced Framingham Risk Score (12% to 2%) After therapy
Zvinovski et al.44 2021 25
Pilot
Hospital-based
14 wk, 60 min/session, 3 days/wk and for a minimum total of 36 sessions. 60%−85% of their VO2max 60 Increased in VO2peak (+0.5 mL/kg/min) and decreased in systolic blood pressure, heart rate, total cholesterol, LDL cholesterol, and fasting glucose After therapy
Toohey et al.45 2020 17
RCT
Hospital-based
12 wk, HIIT at max effort, gradual increase from 4×30 sec/session to 7×30 sec/session, 3 sessions/wk. 12 wk, continuous aerobic training, 20 min/session, 55%−65% of max power, 3 sessions/wk at moderate intensity 78.7 Increased in VO2peak (19.3%) in the HIIT group After therapy

RCT: randomized controlled trial, VO2peak: peak oxygen uptake, VO2max, maximal oxygen uptake; FMD: flow-mediated dilation; HIIT: high-intensity interval training, LDL: low-density lipoprotein.

Korean J Sports Med 2021;39:77-90 https://doi.org/10.5763/kjsm.2021.39.3.77
© 2021 Korean J Sports Med